Revisiones en Cáncer 00050 / http://dx.doi.org/10.20960/revcancer.00050

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Revisión

Quimioterapia en el cáncer de próstata hormono-naïve

David Humberto Marmolejo, Rafael Morales-Barrera, Macarena González, Cristina Suárez, Pablo Cresta, Joaquín Mateo, Joan Carles

Prepublicado: 2024-02-14

Publicado: 2024-03-06

VOLUMEN 37, NÚM. 6, noviembre-diciembre (2023), PAG. 293-301

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El paradigma de tratamiento del cáncer de próstata metastásico ha evolucionado rápidamente en los últimos años. El pilar del tratamiento en la enfermedad metastásica continúa siendo la terapia de deprivación de andrógenos, pero la intensificación del tratamiento con la adición de quimioterapia y de los nuevos inhibidores de la vía del receptor de andrógenos (dobletes y tripletes) han proporcionado mejoras significativas en la supervivencia en el escenario hormono-sensible, retrasando la progresión a la resistencia a la castración y mejorando la calidad de vida de los pacientes. Sin embargo, surgen controversias sobre el beneficio de la terapia de intensificación y la selección óptima del tratamiento según el escenario clínico de cada paciente.

Palabras Clave: Cáncer de próstata. Quimioterapia. Hormonosensible. Metastásico. Docetaxel.

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